| Host: |
Rabbit |
| Applications: |
CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VKORC1 (10-60) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
FITC |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.65-0.70 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:50, 000ELISA: 1:50, 000IP: 1:200IHC: 1:250ICC: 1:250IF: 1:250CFM: 1:250 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Vkorc1 |
| Gene ID: |
309004 |
| Uniprot ID: |
VKOR1_RAT |
| Immunogen Region: |
10-60 |
| Immunogen: |
Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein. |
| Tissue Specificity | Highly expressed in liver. Detected at lower levels in lung, kidney and testis. |
| Function | Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development. |
| Protein Name | Vitamin K Epoxide Reductase Complex Subunit 1Vitamin K1 2 -3-Epoxide Reductase Subunit 1 |
| Database Links | Reactome: R-RNO-6806664 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vitamin K Epoxide Reductase Complex Subunit 1 antibodyAnti-Vitamin K1 2 -3-Epoxide Reductase Subunit 1 antibodyAnti-Vkorc1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
