Anti-VIPR1/VPAC1 antibody [23A11] (STJA0027830)

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STJA0027830
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC/SPR/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Vasoactive Intestinal Polypeptide Receptor 1 for use in FC, SPR and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 23A11
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: VIPR1
Gene ID: 7433
Uniprot ID: VIPR1_HUMAN
Function G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway.
Protein Name Vasoactive Intestinal Polypeptide Receptor 1
Vip-R-1
Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor
Pacap Type Ii Receptor
Pacap-R-2
Pacap-R2
Vpac1 Receptor
Vpac1r
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Vasoactive Intestinal Polypeptide Receptor 1 antibody
Anti-Vip-R-1 antibody
Anti-Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor antibody
Anti-Pacap Type Ii Receptor antibody
Anti-Pacap-R-2 antibody
Anti-Pacap-R2 antibody
Anti-Vpac1 Receptor antibody
Anti-Vpac1r antibody
Anti-VIPR1 antibody

Information sourced from Uniprot.org

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