| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Vasoactive intestinal polypeptide receptor 1 (332-381 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VIPR1 |
| Gene ID: | 7433 |
| Uniprot ID: | VIPR1_HUMAN |
| Immunogen Region: | 332-381 aa |
| Specificity: | VPAC1 Polyclonal Antibody detects endogenous levels of VPAC1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human VIPR1 at the amino acid range 332-381 |
| Function | G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. |
| Protein Name | Vasoactive Intestinal Polypeptide Receptor 1Vip-R-1Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii ReceptorPacap Type Ii ReceptorPacap-R-2Pacap-R2Vpac1 ReceptorVpac1r |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vasoactive Intestinal Polypeptide Receptor 1 antibodyAnti-Vip-R-1 antibodyAnti-Pituitary Adenylate Cyclase-Activating Polypeptide Type Ii Receptor antibodyAnti-Pacap Type Ii Receptor antibodyAnti-Pacap-R-2 antibodyAnti-Pacap-R2 antibodyAnti-Vpac1 Receptor antibodyAnti-Vpac1r antibodyAnti-VIPR1 antibody |
Information sourced from Uniprot.org
