| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VIP |
| Gene ID: | 7432 |
| Uniprot ID: | VIP_HUMAN |
| Immunogen Region: | 1-169 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human VIP (NP_919416.1). |
| Immunogen Sequence: | MDTRNKAQLLVLLTLLSVLF SQTSAWPLYRAPSALRLGDR IPFEGANEPDQVSLKEDIDM LQNALAENDTPYYDVSRNAR HADGVFTSDFSKLLGQLSAK KYLESLMGKRVSNISEDPVP VKRHSDAVFTDNYTRLRKQM AVKKYLNSILNGKRSSEGES PDFPEELEK |
| Function | VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin. |
| Protein Name | Vip Peptides Cleaved Into - Intestinal Peptide Phv-42Peptide Histidine Valine 42 - Intestinal Peptide Phm-27Peptide Histidine Methioninamide 27 - Vasoactive Intestinal PeptideVipVasoactive Intestinal Polypeptide |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Vip Peptides Cleaved Into - Intestinal Peptide Phv-42 antibodyAnti-Peptide Histidine Valine 42 - Intestinal Peptide Phm-27 antibodyAnti-Peptide Histidine Methioninamide 27 - Vasoactive Intestinal Peptide antibodyAnti-Vip antibodyAnti-Vasoactive Intestinal Polypeptide antibodyAnti-VIP antibody |
Information sourced from Uniprot.org