Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-VEGFB (30-207) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
VEGFB |
Gene ID: |
7423 |
Uniprot ID: |
VEGFB_HUMAN |
Immunogen Region: |
30-207 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-207 of human VEGFB (NP_003368.1). |
Immunogen Sequence: |
GHQRKVVSWIDVYTRATCQP REVVVPLTVELMGTVAKQLV PSCVTVQRCGGCCPDDGLEC VPTGQHQVRMQILMIRYPSS QLGEMSLEEHSQ |
Tissue Specificity | Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. |
Post Translational Modifications | VEGF-B186 is O-glycosylated. |
Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
Protein Name | Vascular Endothelial Growth Factor BVegf-BVegf-Related FactorVrf |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-194313Reactome: R-HSA-195399 |
Cellular Localisation | SecretedSecreted But Remains Associated To Cells Or To The Extracellular Matrix Unless Released By Heparin |
Alternative Antibody Names | Anti-Vascular Endothelial Growth Factor B antibodyAnti-Vegf-B antibodyAnti-Vegf-Related Factor antibodyAnti-Vrf antibodyAnti-VEGFB antibodyAnti-VRF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance