Anti-VCAN antibody (532-581 aa) (STJ96239)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human VCAN at the amino acid range 532-581
General Information
| Short Description | Rabbit polyclonal anti-Versican core protein (532-581 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VCAN |
| Gene ID | 1462 |
| Uniprot ID | CSPG2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human VCAN at the amino acid range 532-581 |
| Immunogen Region | 532-581 aa |
| Specificity | Versican Polyclonal Antibody detects endogenous levels of Versican protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. Proteolytically cleaved by ADAMTS5 and ADAMTS15 in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration. |
| Function | May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. |
| Protein Name | Versican Core ProteinChondroitin Sulfate Proteoglycan Core Protein 2Chondroitin Sulfate Proteoglycan 2Glial Hyaluronate-Binding ProteinGhapLarge Fibroblast ProteoglycanPg-M |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-381426Reactome: R-HSA-4420332Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCell ProjectionCiliumPhotoreceptor Outer SegmentInterphotoreceptor Matrix |
| Alternative Antibody Names | Anti-Versican Core Protein antibodyAnti-Chondroitin Sulfate Proteoglycan Core Protein 2 antibodyAnti-Chondroitin Sulfate Proteoglycan 2 antibodyAnti-Glial Hyaluronate-Binding Protein antibodyAnti-Ghap antibodyAnti-Large Fibroblast Proteoglycan antibodyAnti-Pg-M antibodyAnti-VCAN antibodyAnti-CSPG2 antibody |
Information sourced from Uniprot.org