Anti-VAV1 antibody [R06-9Z9] (STJA0037037)

Name: Anti-VAV1 antibody [R06-9Z9] (STJA0037037)
SKU: STJA0037037
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenA synthesized peptide derived from human Vav1/2/3

STJA0037037

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Short Description	Rabbit monoclonal anti-VAV1 for use in WB, ICC, IF, IP and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ICC/IF/IP/FC
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	R06-9Z9
Isotype	IgG
Conjugation	Unconjugated
Purification	Affinity Chromatography
Dilution Range	WB 1:500-1:1000 IF 1:50-1:200 IP 1:50 FC 1:50-1:100
Formulation	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction	Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Gene Symbol	VAV1
Gene ID	7409
Uniprot ID	VAV_HUMAN
Immunogen	A synthesized peptide derived from human Vav1/2/3

Tissue Specificity	Widely expressed in hematopoietic cells but not in other cell types.
Post Translational Modifications	Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.
Function	Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Protein Name	Proto-Oncogene Vav
Database Links	Reactome: R-HSA-114604 Reactome: R-HSA-1257604 Reactome: R-HSA-1433557 Reactome: R-HSA-193648 Reactome: R-HSA-2029482 Reactome: R-HSA-2219530 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-389359 Reactome: R-HSA-416482 Reactome: R-HSA-4420097 Reactome: R-HSA-512988 Reactome: R-HSA-5218920 Reactome: R-HSA-6811558 Reactome: R-HSA-8980692 Reactome: R-HSA-9013149 Reactome: R-HSA-9013404 Reactome: R-HSA-9013408 Reactome: R-HSA-9027284 Reactome: R-HSA-912631 Reactome: R-HSA-9664422 Reactome: R-HSA-9679191 Reactome: R-HSA-9748787 Reactome: R-HSA-983695
Cellular Localisation
Alternative Antibody Names	Anti-Proto-Oncogene Vav antibody Anti-VAV1 antibody Anti-VAV antibody

Information sourced from Uniprot.org