Anti-USP47 antibody (302-352 aa) (STJ195279)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human UBP47 at the amino acid range 302-352
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin carboxyl-terminal hydrolase 47 (302-352 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP47 |
| Gene ID | 55031 |
| Uniprot ID | UBP47_HUMAN |
| Immunogen | Synthesized peptide derived from the human UBP47 at the amino acid range 302-352 |
| Immunogen Region | 302-352 aa |
| Specificity | This antibody detects endogenous levels of UBP47 at Human/Mouse |
Additional Info
| Function | Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 47Deubiquitinating Enzyme 47Ubiquitin Thioesterase 47Ubiquitin-Specific-Processing Protease 47 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 47 antibodyAnti-Deubiquitinating Enzyme 47 antibodyAnti-Ubiquitin Thioesterase 47 antibodyAnti-Ubiquitin-Specific-Processing Protease 47 antibodyAnti-USP47 antibody |
Information sourced from Uniprot.org