| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 47 (302-352 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | USP47 |
| Gene ID: | 55031 |
| Uniprot ID: | UBP47_HUMAN |
| Immunogen Region: | 302-352 aa |
| Specificity: | This antibody detects endogenous levels of UBP47 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human UBP47 at the amino acid range 302-352 |
| Function | Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 47Deubiquitinating Enzyme 47Ubiquitin Thioesterase 47Ubiquitin-Specific-Processing Protease 47 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 47 antibodyAnti-Deubiquitinating Enzyme 47 antibodyAnti-Ubiquitin Thioesterase 47 antibodyAnti-Ubiquitin-Specific-Processing Protease 47 antibodyAnti-USP47 antibody |
Information sourced from Uniprot.org