Anti-USP46 antibody (100-200) (STJ119875)

Name: Anti-USP46 antibody (100-200) (STJ119875)
SKU: STJ119875
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ119875

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Short Description	Rabbit polyclonal USP46 (100-200) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	USP46
Gene ID	64854
Uniprot ID	UBP46_HUMAN
Immunogen Region	100-200
Immunogen Sequence	KKFISRLRKENDLFDNYMQQ DAHEFLNYLLNTIADILQEE KKQEKQNGKLKNGNMNEPAE NNKPELTWVHEIFQGTLTNE TRCLNCETVSSKDEDFLDLS V
Specificity	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human USP46 (NP_073743.2).

Tissue Specificity	Broadly expressed.
Function	Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Protein Name	Ubiquitin Carboxyl-Terminal Hydrolase 46 Deubiquitinating Enzyme 46 Ubiquitin Thioesterase 46 Ubiquitin-Specific-Processing Protease 46
Database Links
Cellular Localisation	Cytoplasm Usp46/Wdr48/Wdr20 Complex Is Predominantly Cytoplasmic
Alternative Antibody Names	Anti-Ubiquitin Carboxyl-Terminal Hydrolase 46 antibody Anti-Deubiquitinating Enzyme 46 antibody Anti-Ubiquitin Thioesterase 46 antibody Anti-Ubiquitin-Specific-Processing Protease 46 antibody Anti-USP46 antibody

Information sourced from Uniprot.org