Host: |
Rabbit |
Applications: |
IHC/IF |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 34 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC-P 1:50-300IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
USP34 |
Gene ID: |
9736 |
Uniprot ID: |
UBP34_HUMAN |
Specificity: |
UBP34 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from part of the human protein |
Function | Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. |
Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 34Deubiquitinating Enzyme 34Ubiquitin Thioesterase 34Ubiquitin-Specific-Processing Protease 34 |
Database Links | Reactome: R-HSA-201681Reactome: R-HSA-5689880 |
Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 34 antibodyAnti-Deubiquitinating Enzyme 34 antibodyAnti-Ubiquitin Thioesterase 34 antibodyAnti-Ubiquitin-Specific-Processing Protease 34 antibodyAnti-USP34 antibodyAnti-KIAA0570 antibodyAnti-KIAA0729 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance