• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-USP34 antibody (STJ191576)

SKU:
STJ191576

Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 34 is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: USP34
Gene ID: 9736
Uniprot ID: UBP34_HUMAN
Specificity: UBP34 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Protein Name Ubiquitin Carboxyl-Terminal Hydrolase 34
Deubiquitinating Enzyme 34
Ubiquitin Thioesterase 34
Ubiquitin-Specific-Processing Protease 34
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-5689880
Alternative Antibody Names Anti-Ubiquitin Carboxyl-Terminal Hydrolase 34 antibody
Anti-Deubiquitinating Enzyme 34 antibody
Anti-Ubiquitin Thioesterase 34 antibody
Anti-Ubiquitin-Specific-Processing Protease 34 antibody
Anti-USP34 antibody
Anti-KIAA0570 antibody
Anti-KIAA0729 antibody

Information sourced from Uniprot.org

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