Anti-USP31 antibody (STJA0010291)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human USP31
General Information
| Short Description | Rabbit polyclonal anti-Ubiquitin carboxyl-terminal hydrolase 31 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP31 |
| Gene ID | 57478 |
| Uniprot ID | UBP31_HUMAN |
| Immunogen | Synthesized peptide derived from human USP31 |
| Specificity | This antibody detects endogenous levels of USP31 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Acetylated at Lys-1264. Acetylation decreases activity. Deacetylated by SIRT1. |
| Function | Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. May play a role in the regulation of NF-kappa-B signaling pathway by deubiquitinating TRAF2. (Microbial infection) Plays a positive role in foot-and-mouth disease and classical swine fever viral infection. Mechanistically, associates with internal ribosomal entry site (IRES) element within the 5'-untranslated region of viral genomes to promote translation of the virus-encoded polyprotein. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 31Deubiquitinating Enzyme 31Ubiquitin Thioesterase 31Ubiquitin-Specific-Processing Protease 31 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 31 antibodyAnti-Deubiquitinating Enzyme 31 antibodyAnti-Ubiquitin Thioesterase 31 antibodyAnti-Ubiquitin-Specific-Processing Protease 31 antibodyAnti-USP31 antibodyAnti-KIAA1203 antibody |
Information sourced from Uniprot.org