Anti-Uroplakin III antibody [SM5064] (STJA0005064)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenSynthesized peptide derived from human Uroplakin III
General Information
| Short Description | Mouse monoclonal anti-Uroplakin III for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM5064 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC/IF (H) 1:200-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | UPK3A |
| Gene ID | 7380 |
| Uniprot ID | UPK3A_HUMAN |
| Immunogen | Synthesized peptide derived from human Uroplakin III |
Additional Info
| Function | Component of the asymmetric unit membrane (AUM).a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. |
| Protein Name | Uroplakin-3aUp3aUroplakin IiiUpiii |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinHeterodimer Formation With Upk1b Is A Prerequisite To Exit Out Of The Endoplasmic Reticulum (Er) |
| Alternative Antibody Names | Anti-Uroplakin-3a antibodyAnti-Up3a antibodyAnti-Uroplakin Iii antibodyAnti-Upiii antibodyAnti-UPK3A antibodyAnti-UPK3 antibody |
Information sourced from Uniprot.org