Anti-UQCC2 antibody (14-126) (STJ112027)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UQCC2 (14-126) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UQCC2 |
| Gene ID | 84300 |
| Uniprot ID | UQCC2_HUMAN |
| Immunogen Region | 14-126 |
| Immunogen Sequence | EEWPVDETKRGRDLGAYLRQ RVAQAFREGENTQVAEPEAC DQMYESLARLHSNYYKHKYP RPRDTSFSGLSLEEYKLILS TDTLEELKEIDKGMWKKLQE KFAPKGPEEDHKA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 14-126 of human UQCC2 (NP_115716.1). |
Additional Info
| Tissue Specificity | Pancreas, skeletal muscle, kidney, liver and heart. |
| Function | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. |
| Protein Name | Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 2Breast Cancer-Associated Protein Sga-81mMitochondrial Nucleoid Factor 1Mitochondrial Protein M19 |
| Database Links | Reactome: R-HSA-9865881 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion NucleoidMitochondrionMitochondrion Intermembrane SpaceMitochondrion Inner MembranePredominantly Expressed In The Mitochondrial Inner Membrane |
| Alternative Antibody Names | Anti-Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 2 antibodyAnti-Breast Cancer-Associated Protein Sga-81m antibodyAnti-Mitochondrial Nucleoid Factor 1 antibodyAnti-Mitochondrial Protein M19 antibodyAnti-UQCC2 antibodyAnti-C6orf125 antibodyAnti-MNF1 antibody |
Information sourced from Uniprot.org