| Host: | Rabbit, Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit, Mouse mix antibody anti-UP II is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Mix |
| Conjugation: | Unconjugated |
| Formulation: | Tissue culture supernatant with sodium azide |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P 1:50-1:100 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | UPII: Peptide-KLH conjugate. UPIII: Raised in mouse using AUM preparation from bovine urinary bladder as the immunogen. |
| Background | Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, Uroplakin II/III cocktail is specific for tumors of urothelial origin and, when used in combination with other markers, can aid in the diagnosis of primary and metastatic tumors. |
Information sourced from Uniprot.org