| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Putative E3 ubiquitin-protein ligase UNKL (296-346 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UNKL |
| Gene ID: | 64718 |
| Uniprot ID: | UNKL_HUMAN |
| Immunogen Region: | 296-346 aa |
| Specificity: | This antibody detects endogenous levels of UNKL at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human UNKL at the amino acid range 296-346 |
| Function | May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven. |
| Protein Name | Putative E3 Ubiquitin-Protein Ligase UnklRing Finger Protein Unkempt-LikeZinc Finger Ccch Domain-Containing Protein 5-Like |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Isoform 4: CytoplasmNucleusIsoform 4 Is Primarily Localized In The Cytoplasm But Has The Ability To Shuttle Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-Putative E3 Ubiquitin-Protein Ligase Unkl antibodyAnti-Ring Finger Protein Unkempt-Like antibodyAnti-Zinc Finger Ccch Domain-Containing Protein 5-Like antibodyAnti-UNKL antibodyAnti-C16orf28 antibodyAnti-ZC3H5L antibodyAnti-ZC3HDC5L antibody |
Information sourced from Uniprot.org