Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-UNC93B1 antibody (347-397 aa) (STJ194377)

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STJ194377
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Protein unc-93 homolog B1 (347-397 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UNC93B1
Gene ID: 81622
Uniprot ID: UN93B_HUMAN
Immunogen Region: 347-397 aa
Specificity: This antibody detects endogenous levels of UN93B at Human/Mouse
Immunogen: Synthesized peptide derived from the human UN93B at the amino acid range 347-397
Post Translational Modifications N-glycosylated.
Function Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.
Protein Name Protein Unc-93 Homolog B1
Unc-93b1
Hunc93b1
Database Links Reactome: R-HSA-1679131
Reactome: R-HSA-5602415
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Endosome
Lysosome
Cytoplasmic Vesicle
Phagosome
Relocalizes From Endoplasmic Reticulum To Endosome And Lysosome Upon Cell-Stimulation With Cpg Dinucleotides
Colocalizes With Lamp5 In Large Endosomal Intracellular Vesicles
Alternative Antibody Names Anti-Protein Unc-93 Homolog B1 antibody
Anti-Unc-93b1 antibody
Anti-Hunc93b1 antibody
Anti-UNC93B1 antibody
Anti-UNC93 antibody
Anti-UNC93B antibody

Information sourced from Uniprot.org

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