Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-UGT1A5 antibody (88-138 aa) (STJ194184)

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STJ194184
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-UDP-glucuronosyltransferase 1A5 (88-138 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UGT1A5
Gene ID: 54579
Uniprot ID: UD15_HUMAN
Immunogen Region: 88-138 aa
Specificity: This antibody detects endogenous levels of UD15 at Human/Rat
Immunogen: Synthesized peptide derived from the human UD15 at the amino acid range 88-138
Function Isoform 1: UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist zolarsatan, a drug which can inhibit the effect of angiotensin II. Isoform 2: Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1.
Protein Name Udp-Glucuronosyltransferase 1a5
Ugt1a5
Udp-Glucuronosyltransferase 1-5
Udpgt 1-5
Ugt1*5
Ugt1-05
Ugt1.5
Udp-Glucuronosyltransferase 1-E
Ugt-1e
Ugt1e
Database Links Reactome: R-HSA-156588
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Udp-Glucuronosyltransferase 1a5 antibody
Anti-Ugt1a5 antibody
Anti-Udp-Glucuronosyltransferase 1-5 antibody
Anti-Udpgt 1-5 antibody
Anti-Ugt1*5 antibody
Anti-Ugt1-05 antibody
Anti-Ugt1.5 antibody
Anti-Udp-Glucuronosyltransferase 1-E antibody
Anti-Ugt-1e antibody
Anti-Ugt1e antibody
Anti-UGT1A5 antibody
Anti-GNT1 antibody
Anti-UGT1 antibody

Information sourced from Uniprot.org

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