| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UDP-glucuronosyltransferase 1A5 (88-138 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UGT1A5 |
| Gene ID: |
54579 |
| Uniprot ID: |
UD15_HUMAN |
| Immunogen Region: |
88-138 aa |
| Specificity: |
This antibody detects endogenous levels of UD15 at Human/Rat |
| Immunogen: |
Synthesized peptide derived from the human UD15 at the amino acid range 88-138 |
| Function | Isoform 1: UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist zolarsatan, a drug which can inhibit the effect of angiotensin II. Isoform 2: Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1. |
| Protein Name | Udp-Glucuronosyltransferase 1a5Ugt1a5Udp-Glucuronosyltransferase 1-5Udpgt 1-5Ugt1*5Ugt1-05Ugt1.5Udp-Glucuronosyltransferase 1-EUgt-1eUgt1e |
| Database Links | Reactome: R-HSA-156588Reactome: R-HSA-9749641 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-Glucuronosyltransferase 1a5 antibodyAnti-Ugt1a5 antibodyAnti-Udp-Glucuronosyltransferase 1-5 antibodyAnti-Udpgt 1-5 antibodyAnti-Ugt1*5 antibodyAnti-Ugt1-05 antibodyAnti-Ugt1.5 antibodyAnti-Udp-Glucuronosyltransferase 1-E antibodyAnti-Ugt-1e antibodyAnti-Ugt1e antibodyAnti-UGT1A5 antibodyAnti-GNT1 antibodyAnti-UGT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
