| Short Description : | Rabbit polyclonal UGDH (165-494) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UGDH |
| Gene ID: | 7358 |
| Uniprot ID: | UGDH_HUMAN |
| Immunogen Region: | 165-494 |
| Immunogen Sequence: | EGTAIKDLKNPDRVLIGGDE TPEGQRAVQALCAVYEHWVP REKILTTNTWSSELSKLAAN AFLAQRISSINSISALCEAT GADVEEVATAIGMDQRIGNK FLKASVGFGGSCFQKDVLNL VYLCEALNLPEVARYWQQVI DMNDYQRRRFASRIIDSLFN TVTDKKIAILGFAFKKDTGD TRESSSIYISKYLMDEGAHL HIYDPKVPREQIVVDLSHPG VSEDDQVSRLVTISKDPYE |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1). |
| Tissue Specificity | Detected in heart, placenta, liver, pancreas, spleen, thymus, prostate, ovary, small intestine and colon. Widely expressed. |
| Function | Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development. |
| Protein Name | Udp-Glucose 6-DehydrogenaseUdp-Glc DehydrogenaseUdp-GlcdhUdpgdh |
| Database Links | Reactome: R-HSA-173599 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Udp-Glucose 6-Dehydrogenase antibodyAnti-Udp-Glc Dehydrogenase antibodyAnti-Udp-Glcdh antibodyAnti-Udpgdh antibodyAnti-UGDH antibody |
Information sourced from Uniprot.org
