Anti-UFM1 antibody (1-63) (STJ118288)

Name: Anti-UFM1 antibody (1-63) (STJ118288)
SKU: STJ118288
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118288

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Short Description	Rabbit polyclonal UFM1 (1-63) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:5000 IHC-P:1:100-1:500 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	UFM1
Gene ID	51569
Uniprot ID	UFM1_HUMAN
Immunogen Region	1-63
Immunogen Sequence	MSKVSFKITLTSDPRLPYKV LSVPESTPFTAVLKFAAEEF KVPAATSAIITNDGIGINPA QTA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human UFM1 (NP_057701.1).

Post Translational Modifications	UFM1 precursor is cleaved by UFSP1, promoting its maturation: processing of the C-terminal Ser-Cys dipeptide is required to expose its C-terminal conserved Gly residue.
Function	Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
Protein Name	Ubiquitin-Fold Modifier 1
Database Links
Cellular Localisation	Nucleus Cytoplasm
Alternative Antibody Names	Anti-Ubiquitin-Fold Modifier 1 antibody Anti-UFM1 antibody Anti-C13orf20 antibody Anti-BM-002 antibody

Information sourced from Uniprot.org