Anti-UCMA antibody (STJA0008791)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human UCMA
General Information
| Short Description | Rabbit polyclonal anti-Unique cartilage matrix-associated protein for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UCMA |
| Gene ID | 221044 |
| Uniprot ID | UCMA_HUMAN |
| Immunogen | Synthesized peptide derived from human UCMA |
| Specificity | This antibody detects endogenous levels of UCMA at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Proteolytically cleaved by a furin-like convertase to generate a persistent C-terminal fragment found in almost the entire cartilage matrix, and affecting osteoblast differentiation. Sulfated on tyrosine residues. |
| Function | May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. |
| Protein Name | Unique Cartilage Matrix-Associated Protein Cleaved Into - Unique Cartilage Matrix-Associated Protein C-Terminal FragmentUcma-CGla-Rich ProteinGrp |
| Database Links | Reactome: R-HSA-8940973 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Unique Cartilage Matrix-Associated Protein Cleaved Into - Unique Cartilage Matrix-Associated Protein C-Terminal Fragment antibodyAnti-Ucma-C antibodyAnti-Gla-Rich Protein antibodyAnti-Grp antibodyAnti-UCMA antibodyAnti-C10orf49 antibody |
Information sourced from Uniprot.org