Anti-UBP1 antibody (264-314 aa) (STJ194363)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human UBIP1 at the amino acid range 264-314
General Information
| Short Description | Rabbit polyclonal anti-Upstream-binding protein 1 (264-314 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBP1 |
| Gene ID | 7342 |
| Uniprot ID | UBIP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human UBIP1 at the amino acid range 264-314 |
| Immunogen Region | 264-314 aa |
| Specificity | This antibody detects endogenous levels of UBIP1 at Human/Mouse |
Additional Info
| Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
| Protein Name | Upstream-Binding Protein 1Transcription Factor Lbp-1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Upstream-Binding Protein 1 antibodyAnti-Transcription Factor Lbp-1 antibodyAnti-UBP1 antibodyAnti-LBP1 antibody |
Information sourced from Uniprot.org