| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-UbcH8/UBE2L6 (1-152aa) for use in ELISA, WB, ICC, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | k1H3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2bk |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-G affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBE2L6 |
| Gene ID: | 9246 |
| Uniprot ID: | UB2L6_HUMAN |
| Immunogen Region: | 1-152aa |
| Accession Number: | NP_004214 |
| Immunogen: | Recombinant human UBE2L6 (1-152aa) purified from E. coli |
| Tissue Specificity | Present in natural killer cells (at protein level). |
| Post Translational Modifications | ISGylated. |
| Function | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. |
| Protein Name | Ubiquitin/Isg15-Conjugating Enzyme E2 L6E2 Ubiquitin-Conjugating Enzyme L6Retinoic Acid-Induced Gene B ProteinRig-BUbch8Ubiquitin Carrier Protein L6Ubiquitin-Protein Ligase L6 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-168928Reactome: R-HSA-5656169Reactome: R-HSA-936440Reactome: R-HSA-977225Reactome: R-HSA-983168Reactome: R-HSA-9833110Reactome: R-HSA-9833482Reactome: R-HSA-9909505 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin/Isg15-Conjugating Enzyme E2 L6 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme L6 antibodyAnti-Retinoic Acid-Induced Gene B Protein antibodyAnti-Rig-B antibodyAnti-Ubch8 antibodyAnti-Ubiquitin Carrier Protein L6 antibodyAnti-Ubiquitin-Protein Ligase L6 antibodyAnti-UBE2L6 antibodyAnti-UBCH8 antibody |
Information sourced from Uniprot.org
