• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Uba2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from 293 cells, treated with UV 5', using Uba2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using UBA2 Polyclonal Antibody. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-UBA2 antibody (591-640 aa) (STJ96159)

SKU:
STJ96159

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SUMO-activating enzyme subunit 2 (591-640 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UBA2
Gene ID: 10054
Uniprot ID: SAE2_HUMAN
Immunogen Region: 591-640 aa
Specificity: UBA2 Polyclonal Antibody detects endogenous levels of UBA2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Uba2 at the amino acid range 591-640
Function The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Protein Name Sumo-Activating Enzyme Subunit 2
Anthracycline-Associated Resistance Arx
Ubiquitin-Like 1-Activating Enzyme E1b
Ubiquitin-Like Modifier-Activating Enzyme 2
Database Links Reactome: R-HSA-3065676
Reactome: R-HSA-3065678
Cellular Localisation Cytoplasm
Nucleus
Shuttles Between The Cytoplasm And The Nucleus
Sumoylation Is Required Either For Nuclear Translocation Or Nuclear Retention
Alternative Antibody Names Anti-Sumo-Activating Enzyme Subunit 2 antibody
Anti-Anthracycline-Associated Resistance Arx antibody
Anti-Ubiquitin-Like 1-Activating Enzyme E1b antibody
Anti-Ubiquitin-Like Modifier-Activating Enzyme 2 antibody
Anti-UBA2 antibody
Anti-SAE2 antibody
Anti-UBLE1B antibody
Anti-HRIHFB2115 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance