| Tissue Specificity | Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. |
| Post Translational Modifications | Phosphorylated on serine and threonine residues. |
| Function | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. |
| Protein Name | Twinfilin-1Protein A6Protein Tyrosine Kinase 9 |
| Database Links | Reactome: R-HSA-9013418Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCytoskeletonDiffuse Cytoplasmic Localization With Perinuclear And G-Actin-Rich Cortical Actin Structures SublocalizationAlso Found At Membrane Ruffles And Cell-Cell Contacts |
| Alternative Antibody Names | Anti-Twinfilin-1 antibodyAnti-Protein A6 antibodyAnti-Protein Tyrosine Kinase 9 antibodyAnti-TWF1 antibodyAnti-PTK9 antibody |
Information sourced from Uniprot.org
