Anti-TULP1 antibody (90-230 aa) (STJ11105980)

SKU:
STJ11105980
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: TULP1
Gene ID: 7287
Uniprot ID: TULP1_HUMAN
Immunogen Region: 90-230 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 90-230 of human TULP1 (NP_001276324.1).
Immunogen Sequence: PKKPLREKSSADLKERRAKA QGPRGDLGSPDPPPKPLRVR NKEAPAGEGTKMRKTKKKGS GEADKDPSGSPASARKSPAA MFLVGEGSPDKKALKKKGTP KGARKEEEEEEEAATVIKKS NQKGKAKGKGKKKAKEERAP S
Tissue Specificity Retina-specific.
Function Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long-term survival of photoreceptor cells. Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells. Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
Protein Name Tubby-Related Protein 1
Tubby-Like Protein 1
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Secreted
Synapse
Detected At Synapses Between Photoreceptor Cells And Second-Order Neurons
Does Not Have A Cleavable Signal Peptide And Is Secreted By An Alternative Pathway
Alternative Antibody Names Anti-Tubby-Related Protein 1 antibody
Anti-Tubby-Like Protein 1 antibody
Anti-TULP1 antibody
Anti-TUBL1 antibody

Information sourced from Uniprot.org