Tissue Specificity | Retina-specific. |
Function | Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long-term survival of photoreceptor cells. Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells. Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. |
Protein Name | Tubby-Related Protein 1Tubby-Like Protein 1 |
Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic SideSecretedSynapseDetected At Synapses Between Photoreceptor Cells And Second-Order NeuronsDoes Not Have A Cleavable Signal Peptide And Is Secreted By An Alternative Pathway |
Alternative Antibody Names | Anti-Tubby-Related Protein 1 antibodyAnti-Tubby-Like Protein 1 antibodyAnti-TULP1 antibodyAnti-TUBL1 antibody |
Information sourced from Uniprot.org