| Short Description : | Rabbit polyclonal TUBGCP5 (100-200) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TUBGCP5 |
| Gene ID: | 114791 |
| Uniprot ID: | GCP5_HUMAN |
| Immunogen Region: | 100-200 |
| Immunogen Sequence: | KEIKTDAHYSILSLLLCLSD SPSNSSYVETPRNKEVEKKD DFDWGKYLMEDEEMDIGPYM DTPNWSEESEEENDQQPLSR EDSGIQVDRTPLEEQDQNRK L |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TUBGCP5 (NP_443135.3). |
| Tissue Specificity | Widely expressed, with highest levels in heart and skeletal muscle and moderate levels in brain. |
| Function | Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. |
| Protein Name | Gamma-Tubulin Complex Component 5Gcp-5 |
| Database Links | Reactome: R-HSA-380270Reactome: R-HSA-380320 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-Gamma-Tubulin Complex Component 5 antibodyAnti-Gcp-5 antibodyAnti-TUBGCP5 antibodyAnti-GCP5 antibodyAnti-KIAA1899 antibody |
Information sourced from Uniprot.org
