| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TUBGCP3 |
| Gene ID: | 10426 |
| Uniprot ID: | GCP3_HUMAN |
| Immunogen Region: | 1-250 |
| Immunogen Sequence: | MATPDQKSPNVLLQNLCCRI LGRSEADVAQQFQYAVRVIG SNFAPTVERDEFLVAEKIKK ELIRQRREADAALFSELHRK LHSQGVLKNKWSILYLLLSL SEDPRRQPSKVSSYATLFAQ ALPRDAHSTPYYYARPQTLP LSYQDRSAQSAQSSGSVGSS GISSIGLCALSGPAPAPQSL LPGQSNQAPGVGDCLRQQLG SRLAWTLTANQPSSQATTSK GVPSAVSRNMTRSRREGDT |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TUBGCP3 (NP_001273207.1). |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. |
| Protein Name | Gamma-Tubulin Complex Component 3Gcp-3Hgcp3Gamma-Ring Complex Protein 104 KdaH104pHgrip104Spindle Pole Body Protein Spc98 HomologHspc98 |
| Database Links | Reactome: R-HSA-380270Reactome: R-HSA-380320 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-Gamma-Tubulin Complex Component 3 antibodyAnti-Gcp-3 antibodyAnti-Hgcp3 antibodyAnti-Gamma-Ring Complex Protein 104 Kda antibodyAnti-H104p antibodyAnti-Hgrip104 antibodyAnti-Spindle Pole Body Protein Spc98 Homolog antibodyAnti-Hspc98 antibodyAnti-TUBGCP3 antibodyAnti-GCP3 antibody |
Information sourced from Uniprot.org
