| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TTK (536-789) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TTK |
| Gene ID: |
7272 |
| Uniprot ID: |
TTK_HUMAN |
| Immunogen Region: |
536-789 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 536-789 of human TTK (NP_003309.2). |
| Immunogen Sequence: |
SSKVFQVLNEKKQIYAIKYV NLEEADNQTLDSYRNEIAYL NKLQQHSDKIIRLYDYEITD QYIYMVMECGNIDLNSWLKK KKSIDPWERKSYWKNMLEAV HTIHQHGIVHSDLKPANFLI VDGMLKLIDFGIANQMQPDT TSVVKDSQVGTVNYMPPEAI KDMSSSRENGKSKSKISPKS DVWSLGCILYYMTYGKTPFQ QIINQISKLHAIIDPNHEIE FPDIPEKDLQDVLKCCLKR |
| Tissue Specificity | Present in rapidly proliferating cell lines. |
| Function | Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Phosphorylates MAD1L1 to promote mitotic checkpoint signaling. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. |
| Protein Name | Dual Specificity Protein Kinase TtkPhosphotyrosine Picked Threonine-Protein KinasePyt |
| Alternative Antibody Names | Anti-Dual Specificity Protein Kinase Ttk antibodyAnti-Phosphotyrosine Picked Threonine-Protein Kinase antibodyAnti-Pyt antibodyAnti-TTK antibodyAnti-MPS1 antibodyAnti-MPS1L1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
