Post Translational Modifications | Autophosphorylated. Ubiquitinated.HSP90 activity negatively regulates ubiquitination and degradation. |
Function | Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. |
Protein Name | Testis-Specific Serine/Threonine-Protein Kinase 1Tsk-1Tsk1Tssk-1Testis-Specific Kinase 1Serine/Threonine-Protein Kinase 22a |
Cellular Localisation | CytoplasmCytoplasmic VesicleSecretory VesicleAcrosomeCell ProjectionCiliumFlagellumIn SpermatozoaPresent In The Sperm Head And In The Flagellum |
Alternative Antibody Names | Anti-Testis-Specific Serine/Threonine-Protein Kinase 1 antibodyAnti-Tsk-1 antibodyAnti-Tsk1 antibodyAnti-Tssk-1 antibodyAnti-Testis-Specific Kinase 1 antibodyAnti-Serine/Threonine-Protein Kinase 22a antibodyAnti-TSSK1B antibodyAnti-SPOGA1 antibodyAnti-SPOGA4 antibodyAnti-STK22A antibodyAnti-STK22D antibodyAnti-TSSK1 antibodyAnti-FKSG81 antibody |
Information sourced from Uniprot.org