| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DENTT (Internal Region) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TSPYL2 |
| Gene ID: |
64061 |
| Uniprot ID: |
TSYL2_HUMAN |
| Immunogen Region: |
Internal Region |
| Specificity: |
Reacts with an internal region of the human DENTT protein. |
| Immunogen: |
Synthetic peptide corresponding to amino acids from an internal region of the human DENTT protein. |
| Post Translational Modifications | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 2Tspy-Like Protein 2Cell Division Autoantigen 1Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4Ctcl-Associated Antigen Se20-4Differentially-Expressed Nucleolar Tgf-Beta1 Target ProteinNuclear Protein Of 79 KdaNp79 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | NucleusCytoplasmEnriched In Transcriptionally Active Regions Of Chromatin In Neurons |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 2 antibodyAnti-Tspy-Like Protein 2 antibodyAnti-Cell Division Autoantigen 1 antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 antibodyAnti-Ctcl-Associated Antigen Se20-4 antibodyAnti-Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein antibodyAnti-Nuclear Protein Of 79 Kda antibodyAnti-Np79 antibodyAnti-TSPYL2 antibodyAnti-CDA1 antibodyAnti-DENTT antibodyAnti-TSPX antibodyAnti-HRIHFB2216 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
