| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-TSPYL2 (441-454) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
TSPYL2 |
| Gene ID: |
64061 |
| Uniprot ID: |
TSYL2_HUMAN |
| Immunogen Region: |
441-454 |
| Accession Number: |
NP_071400.1 |
| Immunogen Sequence: |
SDIDETIHDIKISD |
| Post Translational Modifications | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 2Tspy-Like Protein 2Cell Division Autoantigen 1Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4Ctcl-Associated Antigen Se20-4Differentially-Expressed Nucleolar Tgf-Beta1 Target ProteinNuclear Protein Of 79 KdaNp79 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | NucleusCytoplasmEnriched In Transcriptionally Active Regions Of Chromatin In Neurons |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 2 antibodyAnti-Tspy-Like Protein 2 antibodyAnti-Cell Division Autoantigen 1 antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 antibodyAnti-Ctcl-Associated Antigen Se20-4 antibodyAnti-Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein antibodyAnti-Nuclear Protein Of 79 Kda antibodyAnti-Np79 antibodyAnti-TSPYL2 antibodyAnti-CDA1 antibodyAnti-DENTT antibodyAnti-TSPX antibodyAnti-HRIHFB2216 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
