| Tissue Specificity | Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. |
| Post Translational Modifications | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 2Tspy-Like Protein 2Cell Division Autoantigen 1Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4Ctcl-Associated Antigen Se20-4Differentially-Expressed Nucleolar Tgf-Beta1 Target ProteinNuclear Protein Of 79 KdaNp79 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | NucleusCytoplasmEnriched In Transcriptionally Active Regions Of Chromatin In Neurons |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 2 antibodyAnti-Tspy-Like Protein 2 antibodyAnti-Cell Division Autoantigen 1 antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 antibodyAnti-Ctcl-Associated Antigen Se20-4 antibodyAnti-Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein antibodyAnti-Nuclear Protein Of 79 Kda antibodyAnti-Np79 antibodyAnti-TSPYL2 antibodyAnti-CDA1 antibodyAnti-DENTT antibodyAnti-TSPX antibodyAnti-HRIHFB2216 antibody |
Information sourced from Uniprot.org
