Tissue Specificity | Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. |
Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
Protein Name | Translocator ProteinMitochondrial Benzodiazepine ReceptorPkbsPeripheral-Type Benzodiazepine ReceptorPbr |
Database Links | Reactome: R-HSA-196108 |
Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Translocator Protein antibodyAnti-Mitochondrial Benzodiazepine Receptor antibodyAnti-Pkbs antibodyAnti-Peripheral-Type Benzodiazepine Receptor antibodyAnti-Pbr antibodyAnti-TSPO antibodyAnti-BZRP antibodyAnti-MBR antibody |
Information sourced from Uniprot.org