Anti-TSPO antibody (1-50) (STJ118095)

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STJ118095
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TSPO
Gene ID: 706
Uniprot ID: TSPO_HUMAN
Immunogen Region: 1-50
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-50 of human PBR/PBR/TSPO (NP_000705.2).
Immunogen Sequence: MAPPWVPAMGFTLAPSLGCF VGSRFVHGEGLRWYAGLQKP SWHPPHWVLG
Tissue Specificity Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides.
Protein Name Translocator Protein
Mitochondrial Benzodiazepine Receptor
Pkbs
Peripheral-Type Benzodiazepine Receptor
Pbr
Database Links Reactome: R-HSA-196108
Cellular Localisation Mitochondrion Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Translocator Protein antibody
Anti-Mitochondrial Benzodiazepine Receptor antibody
Anti-Pkbs antibody
Anti-Peripheral-Type Benzodiazepine Receptor antibody
Anti-Pbr antibody
Anti-TSPO antibody
Anti-BZRP antibody
Anti-MBR antibody

Information sourced from Uniprot.org