Anti-TSLP antibody (29-159 aa) [SRM5470] (STJ11107388)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal TSLP (29-159 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5470 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TSLP |
| Gene ID | 85480 |
| Uniprot ID | TSLP_HUMAN |
| Immunogen Region | 29-159 aa |
| Immunogen Sequence | YDFTNCDFEKIKAAYLSTIS KDLITYMSGTKSTEFNNTVS CSNRPHCLTEIQSLTFNPTA GCASLAKEMFAMKTKAALAI WCPGYSETQINATQAMKKRR KRKVTTNKCLEQVSQLQGLW RRFNRPLLKQQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human TSLP (NP_149024.1). |
Additional Info
| Tissue Specificity | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
| Function | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. |
| Protein Name | Thymic Stromal Lymphopoietin |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Thymic Stromal Lymphopoietin antibodyAnti-TSLP antibody |
Information sourced from Uniprot.org