Anti-TSHR/LGR3 antibody [1H7] {FITC} (STJA0028261)

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STJA0028261
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Thyrotropin Receptor is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 1H7
Conjugation: FITC
Isotype: IgG1
Formulation: 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300
Purification: Purified
Concentration: 05 mg/mL
Storage Instruction: Store at 4°C for 12 months Protect from light Do not freeze
Gene Symbol: TSHR
Gene ID: 7253
Uniprot ID: TSHR_HUMAN
Post Translational Modifications Glycosylated. Sulfated. Sulfation on Tyr-385 plays a role in thyrotropin receptor binding and activation.
Function Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
Protein Name Thyrotropin Receptor
Thyroid-Stimulating Hormone Receptor
Tsh-R
Database Links Reactome: R-HSA-375281
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Antibody Names Anti-Thyrotropin Receptor antibody
Anti-Thyroid-Stimulating Hormone Receptor antibody
Anti-Tsh-R antibody
Anti-TSHR antibody
Anti-LGR3 antibody

Information sourced from Uniprot.org

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