TrpRS antibody western blot HeLa lysates STJA0037241

Anti-Tryptophan tRNA Ligase antibody [R01-4H2] (STJA0037241)

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STJA0037241
€160.20 - €337.80
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Short Description :Rabbit monoclonal anti-Tryptophan tRNA Ligase for use in WB, IHC-P and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/FC
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R01-4H2
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
FC 1:50-1:100
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:WARS1
Gene ID:7453
Uniprot ID:SYWC_HUMAN
Immunogen:A synthesized peptide derived from human TrpRS
Post Translational Modifications Proteolytic cleavage generates 2 forms.T1-TrpRS and T2-TrpRS.
Function Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of the tRNA(Trp). Isoform 1: Has no angiostatic activity. T2-TrpRS: Possesses an angiostatic activity but has no aminoacylation activity. Inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. Isoform 2: Has an angiostatic activity.
Protein Name Tryptophan--Trna Ligase - Cytoplasmic
Interferon-Induced Protein 53
Ifp53
Tryptophanyl-Trna Synthetase
Trprs
Hwrs Cleaved Into - T1-Trprs - T2-Trprs
Database Links Reactome: R-HSA-379716
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Tryptophan--Trna Ligase - Cytoplasmic antibody
Anti-Interferon-Induced Protein 53 antibody
Anti-Ifp53 antibody
Anti-Tryptophanyl-Trna Synthetase antibody
Anti-Trprs antibody
Anti-Hwrs Cleaved Into - T1-Trprs - T2-Trprs antibody
Anti-WARS1 antibody
Anti-IFI53 antibody
Anti-WARS antibody
Anti-WRS antibody

Information sourced from Uniprot.org

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