Anti-TRPV2 antibody (STJ13100415)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from rat TRPV2 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-TRPV2 for use in IHC and WB in Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:3000 is recommended. The optimal dilution should be determined by the end user. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Trpv2 |
| Gene ID | 29465 |
| Uniprot ID | TRPV2_RAT |
| Immunogen | A synthetic peptide from rat TRPV2 conjugated to blue carrier protein was used as the antigen. |
| Specificity | Specific for TRPV2. |
Additional Info
| Post Translational Modifications | N-glycosylated. Phosphorylated by PKA. |
| Function | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius.is not activated by vanilloids and acidic pH. |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily V Member 2Trpv2Osm-9-Like Trp Channel 2Otrpc2Stretch-Activated Channel 2bVanilloid Receptor-Like Protein 1Vrl-1 |
| Database Links | Reactome: R-RNO-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmMelanosomeTranslocates From The Cytoplasm To The Plasma Membrane Upon Ligand Stimulation |
| Alternative Antibody Names | Anti-Transient Receptor Potential Cation Channel Subfamily V Member 2 antibodyAnti-Trpv2 antibodyAnti-Osm-9-Like Trp Channel 2 antibodyAnti-Otrpc2 antibodyAnti-Stretch-Activated Channel 2b antibodyAnti-Vanilloid Receptor-Like Protein 1 antibodyAnti-Vrl-1 antibodyAnti-Trpv2 antibodyAnti-Sac2b antibodyAnti-Vrl1 antibody |
Information sourced from Uniprot.org