| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transient receptor potential cation channel subfamily M member 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRPM1 |
| Gene ID: |
4308 |
| Uniprot ID: |
TRPM1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of TRPM1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human TRPM1 |
| Function | Forms nonselective divalent cation-conducting channels which mediate the influx of Na(2+), Ca(2+), Mg(2+), Mn(2+), Ba(2+), and Ni(2+) into the cytoplasm, leading to membrane depolarization. Impermeable to zinc ions. In addition, forms heteromultimeric ion channels with TRPM3 which are permeable for calcium and zinc ions. Essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade. May play a role in metastasis suppression. May act as a spontaneously active, calcium-permeable plasma membrane channel. |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily M Member 1Long Transient Receptor Potential Channel 1Ltrpc1Melastatin-1 |
| Database Links | Reactome: R-HSA-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum MembraneCell ProjectionAxon |
| Alternative Antibody Names | Anti-Transient Receptor Potential Cation Channel Subfamily M Member 1 antibodyAnti-Long Transient Receptor Potential Channel 1 antibodyAnti-Ltrpc1 antibodyAnti-Melastatin-1 antibodyAnti-TRPM1 antibodyAnti-LTRPC1 antibodyAnti-MLSN antibodyAnti-MLSN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
