Post Translational Modifications | Phosphorylation modulates TRPC channel function by regulating the level of TRPC4 at the cell surface and by increasing the association with NHERF1. |
Function | Forms a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. May also be activated by intracellular calcium store depletion. Isoform Beta: Forms a receptor-activated non-selective calcium permeant cation channel. |
Protein Name | Short Transient Receptor Potential Channel 4Trpc4Trp-Related Protein 4Htrp-4Htrp4 |
Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEnhanced Insertion Into The Cell Membrane After Activation Of The Egf ReceptorIsoform Beta: Cell Membrane |
Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 4 antibodyAnti-Trpc4 antibodyAnti-Trp-Related Protein 4 antibodyAnti-Htrp-4 antibodyAnti-Htrp4 antibodyAnti-TRPC4 antibody |
Information sourced from Uniprot.org