| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-TRPC4 for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 1000 is recommended. Recommended incubation time: 2 days at 4C. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Trpc4 |
| Gene ID: | 22066 |
| Uniprot ID: | TRPC4_MOUSE |
| Specificity: | Specific for TRPC4. |
| Immunogen: | A synthetic peptide from mouse TRPC4 conjugated to blue carrier protein was used as the antigen. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Forms a homomeric ion channel or a heteromeric ion channel with TRPC1.the heteromeric ion channel has reduced calcium permeability compared to the homomeric channel. Also permeable to monovalent ions including sodium, lithium and cesium ions. |
| Protein Name | Short Transient Receptor Potential Channel 4Trpc4Capacitative Calcium Entry Channel Trp4Receptor-Activated Cation Channel Trp4 |
| Database Links | Reactome: R-MMU-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 4 antibodyAnti-Trpc4 antibodyAnti-Capacitative Calcium Entry Channel Trp4 antibodyAnti-Receptor-Activated Cation Channel Trp4 antibodyAnti-Trpc4 antibodyAnti-Trrp4 antibody |
Information sourced from Uniprot.org
