| Host: | Rabbit |
| Applications: | WB/IHC-P/IP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Troponin I for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R07-1Z5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IP 1:50 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TNNI1 |
| Gene ID: | 7135 |
| Uniprot ID: | TNNI1_HUMAN |
| Immunogen: | A synthesized peptide derived from human TNNI1 |
| Tissue Specificity | Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. |
| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Protein Name | Troponin I - Slow Skeletal MuscleTroponin I - Slow-Twitch Isoform |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Troponin I - Slow Skeletal Muscle antibodyAnti-Troponin I - Slow-Twitch Isoform antibodyAnti-TNNI1 antibody |
Information sourced from Uniprot.org