Anti-TRMT1 antibody (STJA0009723)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TRMT1
General Information
| Short Description | Rabbit polyclonal anti-tRNA-N2-dimethyltransferase-N2 methyltransferaseG26dimethyltransferase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRMT1 |
| Gene ID | 55621 |
| Uniprot ID | TRM1_HUMAN |
| Immunogen | Synthesized peptide derived from human TRMT1 |
| Specificity | This antibody detects endogenous levels of TRMT1 at Human, Mouse |
Additional Info
| Function | Dimethylates a single guanine residue at position 26 of most nuclear- and mitochondrial-encoded tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. tRNA guanine(26)-dimethylation is required for redox homeostasis and ensure proper cellular proliferation and oxidative stress survival. |
| Protein Name | TrnaGuanine(26-N(2-DimethyltransferaseTrna 2 -2-Dimethylguanosine-26 MethyltransferaseTrna Methyltransferase 1Htrm1Trna(Guanine-26 -N(2-N(2 MethyltransferaseTrna(M(2 -2g26dimethyltransferase |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Isoform 1: MitochondrionIsoform 3: NucleusCytoplasm |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Guanine(26-N(2-Dimethyltransferase antibodyAnti-Trna 2 -2-Dimethylguanosine-26 Methyltransferase antibodyAnti-Trna Methyltransferase 1 antibodyAnti-Htrm1 antibodyAnti-Trna(Guanine-26 -N(2-N(2 Methyltransferase antibodyAnti-Trna(M(2 -2g26dimethyltransferase antibodyAnti-TRMT1 antibody |
Information sourced from Uniprot.org