Anti-TRIM62 antibody (123-173) (STJA0006671)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TRI62 AA range: 123-173
General Information
| Short Description | Rabbit polyclonal anti-E3 ubiquitin-protein ligase TRIM62 (123-173) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIM62 |
| Gene ID | 55223 |
| Uniprot ID | TRI62_HUMAN |
| Immunogen | Synthesized peptide derived from human TRI62 AA range: 123-173 |
| Immunogen Region | 123-173 |
| Specificity | This antibody detects endogenous levels of human TRI62 |
Additional Info
| Function | E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors.leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim62Tripartite Motif-Containing Protein 62 |
| Database Links | Reactome: R-HSA-877300 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim62 antibodyAnti-Tripartite Motif-Containing Protein 62 antibodyAnti-TRIM62 antibody |
Information sourced from Uniprot.org