| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase TRIM58 (355-405 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRIM58 |
| Gene ID: |
25893 |
| Uniprot ID: |
TRI58_HUMAN |
| Immunogen Region: |
355-405 aa |
| Specificity: |
This antibody detects endogenous levels of TRI58 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human TRI58 at the amino acid range 355-405 |
| Function | E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim58Protein Bia2Ring-Type E3 Ubiquitin Transferase Trim58Tripartite Motif-Containing Protein 58 |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim58 antibodyAnti-Protein Bia2 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Trim58 antibodyAnti-Tripartite Motif-Containing Protein 58 antibodyAnti-TRIM58 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
