| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase TRIM58 (355-405 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRIM58 |
| Gene ID: | 25893 |
| Uniprot ID: | TRI58_HUMAN |
| Immunogen Region: | 355-405 aa |
| Specificity: | This antibody detects endogenous levels of TRI58 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human TRI58 at the amino acid range 355-405 |
| Function | E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization. |
| Protein Name | E3 Ubiquitin-Protein Ligase Trim58Protein Bia2Ring-Type E3 Ubiquitin Transferase Trim58Tripartite Motif-Containing Protein 58 |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Trim58 antibodyAnti-Protein Bia2 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Trim58 antibodyAnti-Tripartite Motif-Containing Protein 58 antibodyAnti-TRIM58 antibody |
Information sourced from Uniprot.org