| Host: |
Goat |
| Applications: |
Pep-ELISA/IHC |
| Reactivity: |
Human/Mouse/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-TRIB1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-3.75µg/mlELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
TRIB1 |
| Gene ID: |
10221 |
| Uniprot ID: |
TRIB1_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_079471.1 |
| Immunogen Sequence: |
TSDQIVPEYQEDSD |
| Function | Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase. The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner. Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain. Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity. |
| Protein Name | Tribbles Homolog 1Trb-1G-Protein-Coupled Receptor-Induced Gene 2 ProteinGig-2Skip1 |
| Database Links | Reactome: R-HSA-9031628 |
| Alternative Antibody Names | Anti-Tribbles Homolog 1 antibodyAnti-Trb-1 antibodyAnti-G-Protein-Coupled Receptor-Induced Gene 2 Protein antibodyAnti-Gig-2 antibodyAnti-Skip1 antibodyAnti-TRIB1 antibodyAnti-C8FW antibodyAnti-GIG2 antibodyAnti-TRB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
