Anti-TRIB1 antibody (C-Term) (STJ71535)

SKU:
STJ71535-100

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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Mouse/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-TRIB1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-3.75µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: TRIB1
Gene ID: 10221
Uniprot ID: TRIB1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_079471.1
Immunogen Sequence: TSDQIVPEYQEDSD
Function Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase. The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner. Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain. Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity.
Protein Name Tribbles Homolog 1
Trb-1
G-Protein-Coupled Receptor-Induced Gene 2 Protein
Gig-2
Skip1
Database Links Reactome: R-HSA-9031628
Alternative Antibody Names Anti-Tribbles Homolog 1 antibody
Anti-Trb-1 antibody
Anti-G-Protein-Coupled Receptor-Induced Gene 2 Protein antibody
Anti-Gig-2 antibody
Anti-Skip1 antibody
Anti-TRIB1 antibody
Anti-C8FW antibody
Anti-GIG2 antibody
Anti-TRB1 antibody

Information sourced from Uniprot.org

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