| Host: | Mouse |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Tri-Methyl-Histone H3.1 and Histone H3.2 and Histone H3.3-Lys9 is suitable for use in Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 2E11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:500-1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H3-3A.H3-3BH3C15.H3C14.H3C133020/3021126961/333932/653604H33_HUMANH32_HUMANH31_HUMAN< |
| Specificity: | The antibody detects endogenous Histone H3 (tri methyl K4) protein. |
| Immunogen: | Synthetic Peptide of Histone H3 (Tri Methyl Lys4) |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H3.1Histone H3/AHistone H3/BHistone H3/CHistone H3/DHistone H3/FHistone H3/HHistone H3/IHistone H3/JHistone H3/KHistone H3/L |
| Database Links | Reactome: R-HSA-1266695Reactome: R-HSA-1912408Reactome: R-HSA-201722Reactome: R-HSA-212300Reactome: R-HSA-2299718Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-3214815Reactome: R-HSA-3214841Reactome: R-HSA-3214842Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-3247509Reactome: R-HSA-427359Reactome: R-HSA-427389Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-5334118Reactome: R-HSA-5578749Reactome: R-HSA-5617472Reactome: R-HSA-5625886Reactome: R-HSA-73728Reactome: R-HSA-73772Reactome: R-HSA-8936459Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-912446Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9616222Reactome: R-HSA-977225Reactome: R-HSA-983231 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H3.1 antibodyAnti-Histone H3/A antibodyAnti-Histone H3/B antibodyAnti-Histone H3/C antibodyAnti-Histone H3/D antibodyAnti-Histone H3/F antibodyAnti-Histone H3/H antibodyAnti-Histone H3/I antibodyAnti-Histone H3/J antibodyAnti-Histone H3/K antibodyAnti-Histone H3/L antibodyAnti-H3C1 antibodyAnti-H3FA antibodyAnti-HIST1H3A.H3C2 antibodyAnti-H3FL antibodyAnti-HIST1H3B.H3C3 antibodyAnti-H3FC antibodyAnti-HIST1H3C.H3C4 antibodyAnti-H3FB antibodyAnti-HIST1H3D.H3C6 antibodyAnti-H3FD antibodyAnti-HIST1H3E.H3C7 antibodyAnti-H3FI antibodyAnti-HIST1H3F.H3C8 antibodyAnti-H3FH antibodyAnti-HIST1H3G.H3C10 antibodyAnti-H3FK antibodyAnti-HIST1H3H.H3C11 antibodyAnti-H3FF antibodyAnti-HIST1H3I.H3C12 antibodyAnti-H3FJ antibodyAnti-HIST1H3J antibody |
Information sourced from Uniprot.org
