| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TREML1 |
| Gene ID: | 340205 |
| Uniprot ID: | TRML1_HUMAN |
| Immunogen Region: | 16-162 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1). |
| Immunogen Sequence: | QGIVGSLPEVLQAPVGSSIL VQCHYRLQDVKAQKVWCRFL PEGCQPLVSSAVDRRAPAGR RTFLTDLGGGLLQVEMVTLQ EEDAGEYGCMVDGARGPQIL HRVSLNILPPEEEEETHKIG SLAENAFSDPAGSANPLEPS QDEKSIP |
| Tissue Specificity | Detected in platelets, monocytic leukemia and in T-cell leukemia. |
| Post Translational Modifications | Phosphorylated on tyrosine residues. |
| Function | Cell surface receptor that may play a role in the innate and adaptive immune response. |
| Protein Name | Trem-Like Transcript 1 ProteinTlt-1Triggering Receptor Expressed On Myeloid Cells-Like Protein 1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmSequestered In Cytoplasmic Vesicles In Resting PlateletsTransported To The Cell Surface After Stimulation By ThrombinSoluble Fragments Can Be Released Into The Serum By Proteolysis |
| Alternative Antibody Names | Anti-Trem-Like Transcript 1 Protein antibodyAnti-Tlt-1 antibodyAnti-Triggering Receptor Expressed On Myeloid Cells-Like Protein 1 antibodyAnti-TREML1 antibodyAnti-TLT1 antibodyAnti-UNQ1825 antibodyAnti-PRO3438 antibody |
Information sourced from Uniprot.org