| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRAPPC6B |
| Gene ID: | 122553 |
| Uniprot ID: | TPC6B_HUMAN |
| Immunogen Region: | 1-130 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human TRAPPC6B (NP_803235.1). |
| Immunogen Sequence: | MADEALFLLLHNEMVSGVYK SAEQGEVENGRCITKLENMG FRVGQGLIERFTKDTARFKD ELDIMKFICKDFWTTVFKKQ IDNLRTNHQYLAFTCGLIRG GLSNLGIKSIVTAEVSSMPA CKFQVMIQKL |
| Tissue Specificity | Both isoforms are expressed ubiquitously (at transcript level), isoform 1 being the most predominant. Expressed in the fetal brain and different regions of the adult brain and spinal cord. |
| Function | Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable). |
| Protein Name | Trafficking Protein Particle Complex Subunit 6bTrapp Complex Subunit 6b |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-8876198 |
| Cellular Localisation | Golgi ApparatusCis-Golgi NetworkEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Trafficking Protein Particle Complex Subunit 6b antibodyAnti-Trapp Complex Subunit 6b antibodyAnti-TRAPPC6B antibody |
Information sourced from Uniprot.org