Anti-TRAPPC14 antibody (STJA0009214)

SKU:
STJA0009214
£49.00 - £261.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal anti-Trafficking protein particle complex subunit 14 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRAPPC14
Gene ID: 55262
Uniprot ID: TPC14_HUMAN
Specificity: This antibody detects endogenous levels of C7orf43 at Human, Mouse
Immunogen: Synthesized peptide derived from human C7orf43
Function Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether. TRAPP II complex also has GEF activity toward RAB1A. TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis. Modulates YAP1 activity as transcriptional regulator.
Protein Name Trafficking Protein Particle Complex Subunit 14
Microtubule-Associated Protein 11
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Vesicle
Midbody
During Mitosis
Precedes Alpha-Tubulin In Gap Formation Of Cell Abscission At The Midbody And Is Co-Localized With Plk1 At The Edges Of Microtubules Extensions Of Daughter Cells Post Cytokinesis Abscission
Colocalizes With Rab3ip On Preciliary Vesicles
Alternative Antibody Names Anti-Trafficking Protein Particle Complex Subunit 14 antibody
Anti-Microtubule-Associated Protein 11 antibody
Anti-TRAPPC14 antibody
Anti-C7orf43 antibody
Anti-MAP11 antibody

Information sourced from Uniprot.org

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